2018 · Paper 2 · Question 2 · 6 marks
SaveThere are different types of gene mutation.
Put a tick (✓) in the box next to the statement which describes incorrectly the effect of the mutation in an exon of a gene.
☐ A substitution may not result in a change to the encoded amino acid.
☐ An inversion will result in a change in the number of DNA bases.
☐ A deletion will result in a frame shift.
☐ An addition will result in a frame shift.

Describe how alterations to tumour suppressor genes can lead to the development of tumours.
A type of malignant tumour cell divides every 8 hours.
Starting with one of these cells, how many tumour cells will be present after 4 weeks? Assume none of these cells will die.
Give your answer in standard form.
Answer ______________