2021 · Paper 2 · Question 7 · 8 marks
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HBV infects a liver cell. The liver cell is 25 µm in diameter.
Use Figure 7 to calculate how many times larger in diameter this cell is than HBV. You should use the lipid layer to measure the diameter of HBV.

One method of transferring RNAi molecules into cells involves combining these molecules with a lipid. Suggest why this increases uptake of RNAi molecules into cells.

Using all the information provided, evaluate the use of the two types of RNAi in treating hepatitis B in humans.
Do not refer in your answer to how RNAi reduces HBV replication.
