2022 · Paper 2 · Question 8 · 10 marks
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Calculate how many grams of STZ should be injected into a rat with a mass of 230.45 g. Show your working.
Give your answer in standard form.
Answer ______________ g
Suggest and explain why STZ was injected per unit of body mass.
The scientists concluded that group B rats could be used for studying type II diabetes in humans.
Use all the information and your knowledge of type II diabetes to evaluate this conclusion.
The scientists repeated the investigation using much higher doses of STZ. This led to destruction of pancreatic cells. The scientists concluded that these rats would not be suitable for studying type II diabetes.
Give two reasons why the scientists made this conclusion.
1
2