2024 · Paper 1 · Question 6 · 8 marks
SaveGive three structural differences between an mRNA molecule and a tRNA molecule.
mRNA ______________ tRNA
Table 3 shows mRNA codons and the amino acid coded by each codon.
Figure 5 shows the mRNA base sequence produced when part of a gene coding for an enzyme is transcribed.
UUU CGG GCG
Use Table 3 to give the amino acids coded by the mRNA base sequence in Figure 5.

A mutation occurred in the part of the gene transcribed in Question 06.2.
Figure 6 shows the mRNA base sequence produced when the identical part in the mutated gene is transcribed.
UUU AGG GCG
The amino acids coded by this mRNA base sequence form part of the enzyme's active site.
Use all the information in this question to:
• name the type of mutation that occurred to produce the mutated gene • give the change in DNA caused by this mutation • explain the effect this mutation will have on the function of the enzyme.
Type of mutation
Change in DNA
Explanation of effect on function of enzyme
