SPEC 8461 · MODULE 1 · CELL BIOLOGY
Eukaryotes, Prokaryotes & Cell Types
In June 2024, students were asked to name a sub-cellular structure in a plant cell. The mark scheme accepted only one answer: "(permanent) vacuole." Students who wrote "fluid sac" or "water store" scored zero. In 10 minutes, you'll know every named structure — in exam wording.
Learning Objectives
By the end of this lesson, you'll be able to:
Identify and compare the sub-cellular structures of eukaryotic and prokaryotic cells
Explain the differences between animal cells, plant cells, and bacterial cells — including structures unique to each
Use the correct AQA mark-scheme wording for every sub-cellular structure
Spec Ref & Paper
Spec 4.1.1.1–4.1.1.2 · Paper 1 · Higher Tier. Cell structure questions appear on every Paper 1. Getting terminology right is the difference between 0 and full marks.
Two Types of Cell
Every living organism has cells that are either eukaryotic or prokaryotic. This distinction is the foundation of all of Module 1.
EUKARYOTIC
A cell whose genetic material is enclosed in a nucleus.
Includes: animal cells, plant cells, fungal cells, and protist cells. Typically 10–100 µm in size.
PROKARYOTIC
A cell whose genetic material is NOT enclosed in a nucleus — it is a single DNA loop in the cytoplasm.
May also have small extra rings of DNA called plasmids. Bacteria are prokaryotic. Typically 1–10 µm — much smaller than eukaryotic cells.
Mark-Scheme Language
For prokaryotes, the mark scheme credits "single loop of DNA" or "single circular DNA molecule." Do NOT write "circular chromosome" — bacterial DNA is not packaged into chromosomes.
Animal Cell
Most animal cells are eukaryotic and share the same five sub-cellular structures — all five appear in exam diagrams for identification and function questions.
Why "Most"?
The AQA spec says "most animal cells" — not all. Some specialised cells lack certain structures. Red blood cells, for example, have no nucleus. Learn the five as the standard set, and note that exceptions exist.
Animal Cell — 5 Structures
Five structures. Every one is examinable for both name and function. Learn both together.
StructureFunction — mark-scheme wording
NucleusContains chromosomes (DNA); controls the cell's activities
CytoplasmJelly-like substance; site of most chemical reactions
Cell membranePartially permeable; controls what enters and leaves the cell
MitochondriaSite of aerobic respiration; releases energy from glucose
RibosomesSite of protein synthesis
Energy Language — All Series
Mark schemes explicitly reject "energy is produced / made / created." Always write "energy is released" or "energy is transferred."
Common Misconception
Plants have mitochondria too. Plant cells photosynthesise AND respire — they need mitochondria to release energy for cell processes, exactly like animal cells. Examiner reports flag this error every series.
Plant Cell
Plant cells have all 5 animal cell structures, plus 3 extra. The large central space (vacuole) and thick outer border (cell wall) are the key visual identifiers.
Plant Cell — 8 Structures
Plant cells have everything animal cells have, plus three additional structures. Algal cells are treated identically by AQA.
Shared with Animal Cells (5)
Nucleus
Cytoplasm
Cell membrane
Mitochondria
Ribosomes
Plant Only — 3 Extra
Cell wall — made of cellulose; strengthens the cell
Permanent vacuole — filled with cell sap; maintains turgor
Chloroplasts — contain chlorophyll; site of photosynthesis — only in green parts of the plant (e.g. leaf cells, not root cells)
"Permanent Vacuole" — Mark-Scheme Alert
Both words matter. Animal cells can have small temporary vacuoles. "Permanent" distinguishes the plant cell structure. "Fluid sac" and "water store" score zero — they describe but do not name.
Bacterial Cell (Prokaryotic)
Bacteria are prokaryotes — no nucleus. Smaller than eukaryotic cells (1–10 µm). Three features unique to bacteria: DNA loop, plasmids, and cell wall made of a non-cellulose polymer.
Bacterial Cell Structures
Know what is present, what is absent, and how to write the DNA description correctly.
Present in Bacteria
Cell wall — different polymer to plant cellulose
Cell membrane — same function as eukaryotes
Cytoplasm — same function
Single circular DNA molecule — in the cytoplasm, not in a nucleus
Plasmids — small extra rings of DNA
Ribosomes — protein synthesis (smaller than eukaryotic ribosomes)
Absent in Bacteria
No nucleus
No mitochondria
No chloroplasts
No permanent vacuole
Key Trap
Never write "bacterial cell wall is made of cellulose." Plant cell walls → cellulose. Bacterial cell walls → different polymer (you don't need to name it).
Cell Type Comparison
StructureAnimal CellPlant CellBacterial Cell
Nucleus✔✔✘ (DNA loop instead)
Cell membrane✔✔✔
Cytoplasm✔✔✔
Ribosomes✔✔✔ (smaller)
Mitochondria✔✔✘
Cell wall (cellulose)✘✔✘ (diff. polymer)
Permanent vacuole✘✔✘
Chloroplasts✘✔ (green parts)✘
DNA loop + plasmids✘✘✔
4 Features All Cells Share
Every cell — animal, plant, or bacterial — has these four: cell membrane, cytoplasm, ribosomes, and genetic material (DNA). This is the answer to any "give a similarity between prokaryotic and eukaryotic cells" question.
Worked Example
A diagram shows a plant cell with three parts labelled X, Y and Z. Part X is the large fluid-filled space inside the cell. Part Y is the outer rigid layer surrounding the cell. Part Z contains the cell's chromosomes.
Name parts X, Y and Z.3 MARKS
Pattern — Recall (AO1)
Step 1: The command word is "name" — write the named term exactly. Descriptions score zero.
Step 2: Match each description to its structure: large fluid-filled space = permanent vacuole; outer rigid layer = cell wall; contains chromosomes = nucleus.
Step 3: Use AQA wording — "permanent vacuole" not "fluid sac." "Cell wall" not "outer casing."
X
(permanent) vacuole — "Vacuole" alone is accepted. "Fluid sac" or "water store" score zero.
Y
cell wall — must say "cell wall," not just "wall" or "outer layer."
Z
nucleus — the structure that contains chromosomes and controls the cell's activities.
Examiner Alerts
Three errors flagged repeatedly across multiple series. Learn these now.
Alert 1 — Describing Instead of Naming
When the question says "name the structure," write the named term. Descriptions like "fluid sac" and "water store" describe the vacuole but do not name it — they score zero regardless of how accurate they are biologically.
Alert 2 — Bacterial Cell Wall = Cellulose
Never write this. Plant cell walls are made of cellulose. Bacterial cell walls use a different polymer. The spec does not require you to name it — but you must never use "cellulose" for bacteria.
Alert 3 — DNA vs Chromosome vs Gene
These three terms are NOT interchangeable. DNA is the molecule. A chromosome is a long coiled strand of DNA (found in eukaryotic nuclei). A gene is a section of a chromosome that codes for a specific protein. Mark schemes are strict — use the correct level of term for the question asked. For bacteria: write "single loop of DNA" not "chromosome" — bacterial DNA is not packaged into chromosomes.
Common Errors
Pause and screenshot. The most frequent mark-losing errors on this topic across 12 papers.
✗ Wrong
"plants don't have mitochondria" / "only animal cells respire"
✓ Correct
Plants do have mitochondria — they photosynthesize AND respire continuously
✗ Wrong
"fluid sac" or "water store" for the large plant cell space
✓ Correct
"(permanent) vacuole" — the named term only
✗ Wrong
"powerhouse of the cell" for mitochondria
✓ Correct
"mitochondria — site of aerobic respiration; releases energy"
✗ Wrong
"bacterial cell wall is made of cellulose"
✓ Correct
"bacterial cell wall — different polymer, NOT cellulose"
✗ Wrong
"bacteria have a nucleus" or "bacteria have a small nucleus"
✓ Correct
"bacteria have no nucleus — DNA is a single loop in the cytoplasm"
Three Things to Remember
Three takeaways. You're set for any cell-identification question on Paper 1.
1. Eukaryotic vs Prokaryotic
Eukaryotic cells (animal, plant, algal, fungal) have a nucleus. Prokaryotic cells (bacteria) have no nucleus — DNA is in a single loop in the cytoplasm, plus possible plasmids.
2. The Structure Lists
Animal: nucleus, cytoplasm, cell membrane, mitochondria, ribosomes. Plant: those 5 plus cell wall (cellulose), permanent vacuole, chloroplasts. Bacteria: cell wall (not cellulose), membrane, cytoplasm, DNA loop, plasmids, ribosomes.
3. Mark-Scheme Wording Matters
Write "permanent vacuole" not "fluid sac." Write "releases energy" not "produces energy." Write "single loop of DNA" not "circular chromosome" for bacteria. Use the AQA term — not a description.
Summary
Three Cell Types — Key Differences
Animal cells: eukaryotic · nucleus · no cell wall · no chloroplasts · no permanent vacuole
Plant cells: eukaryotic · nucleus · cellulose cell wall · permanent vacuole · chloroplasts (green parts)
Bacterial cells: prokaryotic · no nucleus · DNA loop + plasmids · cell wall (not cellulose) · no mitochondria
Algal cells: treated same as plant cells by AQA — chloroplasts, cell wall, permanent vacuole
Wording to Memorise
"(permanent) vacuole" — not "fluid sac" or "water store"
"releases energy" — not "produces / makes / creates energy"
"single loop of DNA" — not "circular chromosome" for bacteria
"different polymer" for bacterial cell wall — not "cellulose"
Next Lesson
Lesson 1.02 — Specialised Cells. Sperm, nerve, muscle, root hair, xylem, phloem — how each cell's structure is adapted to its function. The feature-function link is the mark.
Next: Learning Objectives